Massachusetts Host-Microbiome Center Microbiome Fellowship Openings
2/1/2017: The Bry lab in the Massachusetts Host-Microbiome Center at BWH/Harvard Medical School has two microbiome fellowship openings. The fellow positions will define effects of the microbiota in immunomodulation and pathogen defense, with capacity to develop clinical/therapeutic applications from findings. Systems studied include interactions among the commensal microbiota and multi-drug resistant pathogens, C. difficile, and immunodulatory functions of commensal anaerobes in vivo.
The position will work with defined microbial consortia in in vitro systems and in gnotobiotic (germ free) mice. Analyses will incorporate bacterial strains and microbiome datasets from human populations. The fellow
will also utilize genetic systems to manipulate component species to identify gene targets that mediate desired effects in vivo.
The position offers a unique opportunity to work with world-class scientists in microbiology, computational biology, immunology, pathogenesis and gastroenterology, and to further develop skills in bacterial genomics, synthetic biology, anaerobic microbiology, metagenomics, gnotobiotic animal models, and application of the microbiome to human disease.
Applicants must have US Citizenship, green card or existing work-visa status for the US, and must be within 3 years of completing their PhD or of completing their MD or residency training. To apply, please submit your CV with a cover letter responsive to this posting, detailing your relevant skills, background, and long-term career goals to:
Lynn Bry, MD, PhD
Director, Massachusetts Host-Microbiome Center
Associate Professor, Dept. Pathology
Brigham & Women’s Hospital
Harvard Medical School
Boston, MA 02115
1. PhD in microbiology or related field of biomedical science
2. At least 2 years of graduate or post-graduate experience in microbiology
3. At least 2 years of graduate or post-graduate experience with gene cloning and/or transposon mutagenesis systems in one or more prokaryotic species
4. Candidates must have US citizenship, green card or appropriate work-visa status for the US
1. Experience growing anaerobic species.
2. Molecular biology and/or experience with microbial genetic systems.
3. Excellent analytical, critical thinking and organizational skills. The position will evaluate multiple sources of information, from microbiologic, metabolite and metagenomic datasets analyzed with the computational fellows.
4. Excellent oral and written communication skills. The fellow will work with technical and computational staff, and will provide information in written and oral form to guide the project and development of functional communities for in vivo applications.
5. Willingness to learn the Linux operating system or prior experience working in the Linux environment. The position will work with project bioinformaticians and computational biologists and will be an essential member of the team involved in post-bioinformatic analyses of microbiome datasets. Training will be provided for candidates with robust microbiology experience who wish to gain skills in this area.
6. Experience working with continuous chemostat fermenters and/or animal models a plus, but not required. Training is provided to develop skills in these areas.
7. Experience working with in vitro systems of cellular immunology a plus but not required. Training will be provided to develop skills in this area.