The Gut Microbiome Predicts Graft versus Host Disease after Allogeneic Transplant. Can it be Engineered to Protect?

Seminar Details
Wednesday, March 20, 2019 - 9:00am to 10:00am

Speaker

Jonathan Golob, M.D., Ph.D.
Assistant Professor
Division of Infectious Diseases
Michigan Medicine

Location

5623 Med. Sci. II  (Wheeler Seminar Room)

Multiple studies have correlated the structure and composition of the gut microbiome with the risk of graft versus host disease after allogeneic hematopoietic cell transplant. Follow-up studies have pointed to possible mechanisms driving this correlation. The promise now is to manipulate the gut microbiome after transplant to improve outcomes.