Paving New Roads in Research on the Bacterial Microbiome and Colorectal Cancer

Seminar Details
Wednesday, February 15, 2017 - 9:00am to 10:00am


Marc Sze, Ph.D.
Postdoctoral Research Fellow - Schloss Lab
Department of Microbiology and Immunology


5623 Med. Sci. II  (Wheeler Seminar Room)

Colorectal cancer (CRC) continues to be a worldwide health problem with early detection being used as a key component in mitigating deaths due to the disease.  Previous research suggests a link between fecal bacterial microbiome and CRC. The overall objective of our study was to investigate the changes in the bacterial microbiome  after surgery in patients with lesion (i.e. adenoma or carcinoma). Specifically, we wanted to identify what within the community was different within those undergoing surgical removal of lesion. We also wanted to investigate the use of the bacterial microbiome and Fecal Immunoglobulin Test (FIT) to build models which could classify individuals as having a lesion or as before surgery.  During this talk I will also be discussing one of the ways we plan to build on these findings and research by using both a family based approach and longitudinal study design.

Sponsored by the Host Microbiome Initiative