Seminars

September 30, 2020
9:00 am to 10:00 am

Virtual Seminar via BlueJeans: https://bluejeans.com/880410398/9042

Use passcode: 9042

 

Gustavo Caballero-Flores, Ph.D.
Postdoctoral Fellow
Department of Pathology and Rogel Cancer Center
Michigan Medicine

The microorganisms naturally inhabiting the gastrointestinal tract, collectively known as the gut “microbiota”, serve as a natural barrier to prevent the invasion and expansion of pathogens, a function termed “colonization resistance”. Several processes have been proposed to explain such a host protection conferred by the microbiota including induction of immune responses, reduction of luminal oxygen, and production of microbiota-derived inhibitory compounds.

October 21, 2020
9:00 am to 10:00 am

Seminar access via BlueJeans web conferencing: https://bluejeans.com/637582081/1186

Participant passcode: 1186

Gen Li, PhD
Assistant Professor
Department of Biostatistics, School of Public Health
University of Michigan, Ann Arbor

Microbiome studies offer important potential to identify organisms associated with human disease. Longitudinal measures may further reveal the dynamics of the microbiome and its accumulating effects on health outcomes. However, microbiome data are complex in nature, involving high dimensionality, compositionality, zero inflation and taxonomic hierarchy. This complexity cannot be adequately addressed using existing statistical methods, leaving the power of microbiome data relatively unharnessed.