Microbiology & Immunology

Calcium Signaling in Toxoplasma gondii: How intracellular and Extracellular Calcium Pools Synergize to Cause Disease

Tuesday, September 17, 2019 - 9:45am to 10:45am
Silvia Moreno, Ph.D.
Distinguished Research Professor
Department of Cellular Biology
Center for Tropical and Emerging Global Diseases
University of Georgia

Refreshments served at 9:30 AM

Dissertation Seminar - Regulation and Substrate Selectivity of Peptide Exporters and Their Functional Significance in Streptococcus pneumoniae

Thursday, August 15, 2019 - 2:00pm to 3:00pm
Charles Wang
MSTP graduate student (Dawid Lab)
Department of Microbiology and Immunology
University of Michigan

Peptidase-containing ABC transporters (PCATs) are a widely distributed family of transporters which export peptide substrates containing a double-glycine motif (GG peptides). In gram-positive bacteria, PCATs secrete pheromones used for cell-to-cell signaling and antimicrobial peptides called bacteriocins used for interbacterial killing and competition. PCATs recognize GG peptides through their N-terminal signal sequences, but little is known about how PCATs distinguish between different GG peptides.